Hélène Jacquot-Guimbal studied at the Ecole Normale Supérieure and holds a PhD in Theoretical Physics from Sorbonne University and an engineering degree from the Ecole des Ponts ParisTech. She is a general engineer of Bridges, Waters and Forests at the Université Gustave Eiffel. From 2008 to 2019, she was executive director of the Laboratoire Central des Ponts et Chaussées and then of the French Institute of Science and Technology for Transport, Development and Networks (IFSTTAR), which merged with the Université Paris-Est Marne-la-Vallée to create the Université Gustave Eiffel on 1 January 2020, in partnership with three engineering schools: ESIEE Paris, ENSG, EIVP and an architecture school, Eav&t. She was president of the university in the first year of its creation. Since 29 January 2021, she has been a member of the Conseil d'Orientation des Infrastructures (COI).